Group Leader

Prof. Dr. Steven Verhelst
StevenVerhelstVerhelst received his PhD in Chemistry at Leiden University and performed post-doctoral research at the Stanford University, School of Medicine. He started his own laboratory at the Technical University Munich as an Emmy Noether group leader in 2008. In 2014, he moved to the Leibniz Institute for Analytical Sciences ISAS in Dortmund, Germany, as a group leader in chemical proteomics. Since 2015, he is also appointed as associate professor in chemical biology at the Department of Cellular and Molecular Medicine of the University of Leuven, Belgium.

Research interests
chemical proteomics, activity-based probes, solid phase synthesis, proteases, intramembrane proteases, bioorthogonal chemistry.

Other interests
(molecular) cooking, reading & writing fiction, travelling, listening to heavy metal music, and watching movies from Paul Verhoeven, Quentin Tarantino or Joel & Ethan Coen.

A CV can be found here

Post-doctoral fellows

Dr. Marta Barniol i Xicota (at KU Leuven)
obtained a PhD in Medicinal Chemistry from the University of Barcelona, Spain. She joined the Verhelst laboratory in February 2017.

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Dr. Minh Nguyen (at ISAS)
received her PhD at Heidelberg University, Germany in 2014. In her PhD she worked in the lab of Prof. Matthias Mayer, Center of Molecular Biology Heidelberg (ZMBH) on post-translational modifications of heat shock protein 90 (Hsp90). She’s interested in applications of MS for studying protein dynamics, quantitation and activity. In 2015, she joined the Verhelst Laboratory.

PhD Students

Suravi Chakrabarty (at KU Leuven)
obtained a MSc in Medicinal Chemistry from the Duquesne university, Pittsburgh, PA, USA. She started her PhD in Verhelst laboratory in October 2016.

Suyuan Chen (at ISAS)
obtained a MSc from the Chengdu Institute of Biology, Chinese Academy of Sciences. He received a CSC fellowship and joined the lab in Dortmund in September 2017.

Jan Pascal Kahler (at KU Leuven)
received his MSc in Chemistry from Technische Universitaet Darmstadt, Germany. For his Master thesis he worked in the laboratory of Prof. Dr. Boris Schmidt in the field of medicinal chemistry, aiming to develop new kinase inhibitors. He started his PhD in the Verhelst lab in march 2017.

Merel van de Plassche (at KU Leuven)
received her Msc in Drug Innovation from Utrecht University in the Netherlands. During her masters she worked in the Chemical Biology and Drug Discovery under supervision of Prof. Dr. R.J. Pieters, and at the Suga Laboratory at Tokyo University. She started her PhD in the Verhelst Laboratory in November 2016.

Tim Van Kersavond (at ISAS)
received his MSc in Chemistry from Ghent University, Belgium. For his Master thesis he worked in the laboratories of Prof. Dr. José Martins and Prof. Dr. Annemieke Madder. He started his PhD in the Verhelst Laboratory in 2015.

Jian Yang (at KU Leuven)
obtained a MSc in Chemistry from Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences. He obtained a CSC fellowship and joined the Verhelst laboratory in September 2016.

Scientific co-workers

Roeland Vanhoutte (at KU Leuven)
obtained a Master degree in Drug Development at the KU Leuven. His MSc thesis was performed in the group of Prof. Eveline Lescrinier of the Laboratory for Medicinal Chemistry. He started working in the Verhelst lab in March 2017.

Undergraduate Students

Currently, there are vacancies for undergraduates in our laboratory

Raphael Konopatzki (at ISAS)
studies Molecular Biology at the Westfälische Hochschule in Recklinghausen and joined our lab in Dortmund in September 2017 for an internship and a MSc thesis.

Claudia Perpina (at KU Leuven)
is a student at the faculty of pharmacy of the University of Barcelona, Spain. She joined our lab as an ERASMUS student in September 2017.

Cole Pollina (at KU Leuven)
studies at the University of Denver in the pre-medical track with a double major in Physics and Chemistry and a double minor in Mathematics and Biology. He joined our lab in September 2017 in the framework of the EuroScholars Program.

Alumni

Graduate students

Oliver Vosyka
studied Biology at Ludwigs-Maximilians-Universität München. In the Verhelst Lab, he worked on novel assays to monitor rhomboid protease activity. He obtained his PhD at the Technical University of Munich summa cum laude in September 2013.

Ute Haedke
studied Biochemistry at University of Potsdam, Germany. For her diploma thesis she went to the Laboratory of Dr. Monique Lavialle (INRA Jouy-en-Josas, France). She worked on the development of novel serine protease ABPs and obtained her PhD in December 2013 at the Technical University of Munich.

Sevnur Serim
studied Chemistry at the Technical University of Istanbul, Turkey. She received a Master’s degree at the Technical University of Braunschweig, Germany. For her Master thesis she worked in the Laboratory of Dr. Jürgen Seibel. She obtained her PhD at the Technical University Munich in March 2014 on the topic of the development of novel serine protease ABPs.

Yinliang Yang
studied Biochemistry at Lanzhou University, China, and joined our laboratory with a fellowship from the Chinese Scholarship Council. His doctoral work was focused on the development of novel cleavable linkers for proteomics applications. He obtained his PhD degree at the Technical University of Munich in April 2014.

Eliane Wolf
obtained her Bachelors degree in Molecular Biotechnology from the Technische Universität Dresden and her Masters degree in Molecular Biotechnology at the Technische Universität München with a major in protein biochemistry and protein engineering as well as food biotechnology. In our laboratory, Eliane worked on new assays for rhomboid proteases and the discovery of novel inhibitors.

Undergraduate students

Olga Lagutina
studied Chemical Biology at the Technical University Dortmund and joined the Verhelst Lab for a Master’s thesis.

Annett Zeissler
studied molecular biotechnology at the Technical University Munich and joined our group for a Master’s thesis.

Susanne Mayer
Biochemistry student of the Technical University Munich. She joined our group for a Master’s thesis.

Peter Graf
Biology student at the Technical University Munich. He joined our group for a Master’s thesis and continued his career with his PhD studies.

Philipp Baer
Biochemistry student at the Technical University Munich. He joined our group for a Master’s thesis and moved on to perform his PhD in Michael Groll’s lab.

Andreas Lehr
Biology student at the TU Munich. He did his Bachelors work in our lab.

Fabian Hansen
Biology student at the TU Munich. He worked in the lab for his Master’s thesis.

Veronika Sachsenhauser
student Biology at the TU Munich. She performed her Bachelors work in our lab.

Kerstin Pflieger
Biochemistry student at the TU Munich. She performed her Bachelors work in our lab.

Jonas Lohse
joined the lab for a Bachelor’s thesis during his studies in molecular biotechnology at the TU Munich. He later moved on to pursue his PhD at the University of Groningen, The Netherlands.

Eliane Wolf
performed her Master’s degree in Molecular Biotechnology at the TU Munich and joined the lab for a Master’s thesis.

Emel Diraz
worked in our lab as an Erasmus-exchange student during her Biology Masters in Turkey.

Sandra Frommel
joined our lab for a Bachelor’s thesis during her biology studies at the TU Munich. She later pursued her PhD at the University of Zürich.