BMCL2018

Jian Yang’s paper on benzoxazinones as novel rhomboid inhibitors has been accepted for pubblication in Bioorganic & Medicinal Chemistry Letters. Congrats!

Two other papers on rhomboid inhibitors have recently also appeared with collaboration from Minh Nguyen of our lab. The research group of Dr. Kvido Strisovsky reported on ketoamides as potent, selective, modular and reversible rhomboid inhibitors. The research group of Prof. Sascha Weggen found N-methylene saccharins as novel rhomboid inhibitors. We expect that with these new scaffolds, study of rhomboid function in cellular environment will become easier.

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